This family incorporates only one protein, SET7/9, which mono-methylates histone at H3K4 92 KMT7 was discovered to methylate, moreover histone, a variety of non-histone proteins, including p53, DNA methyltransferase 1 (DNMT1), estrogen receptor alpha (ERα), nuclear factor kappaB (NFκB), and parts of the TATA binding protein (TBP) advanced, TBP-related factors TAF10 and TAF7 93 The …